The Absolute Best Podcasts on YouTube in 2025

You’re scrolling through YouTube, looking for something worth your time. Maybe you’re after a podcast that makes you think, or you need a laugh to get through the day. But with so much content out there, finding the right one can be a headache.

That’s why this list is here—to help you skip the frustration and dive straight into some of the best podcasts YouTube has to offer.

Whether you’re curious about neuroscience, interested in entrepreneurship, or just want a good conversation, these shows deliver content that feels genuine and engaging.

1) Best Long-Form Interview Podcast: The Joe Rogan Experience

Ever wonder what a conversation would be like if it went on for hours without filters? “The Joe Rogan Experience” brings raw, unedited dialogue between Joe and a mix of guests from all walks of life—comedians, scientists, athletes, and thinkers. The beauty of this podcast is in its unpredictability, as it often veers into unexpected, insightful territory. You’ll laugh, you’ll learn, and you’ll probably be left with more questions than answers, which is exactly what makes it stand out.

2) Best Neuroscience and Health Podcast: Huberman Lab

Andrew Huberman delivers neuroscience straight to your ears in “Huberman Lab,” breaking down complex topics like brain function, sleep, and stress in ways that are easy to digest. This podcast stands out because of its balance between cutting-edge science and practical advice. If you’re curious about how your brain shapes your daily life—and how you can optimize it—this is your go-to. You’ll walk away feeling more in control of your health and well-being.

3) Best AI and Technology Podcast: Lex Fridman Podcast

In the “Lex Fridman Podcast,” Lex invites some of the brightest minds in AI, robotics, and technology for deep, thoughtful discussions. If you’re fascinated by the future and the ethical dilemmas we’ll face, this podcast gives you a front-row seat to the minds shaping tomorrow. It’s a space for introspection and big ideas.

4)Best True Crime Podcast: Rotten Mango

“Rotten Mango” is where true crime meets storytelling at its finest. Stephanie Soo crafts gripping, sometimes chilling narratives that make you feel like you’re uncovering the mystery right alongside her. What sets it apart is the focus on both well-known and obscure cases, adding layers of suspense. If you’re a fan of intrigue, justice, and the darker side of human nature, you’ll be hooked from the very first episode.

5) Best Entrepreneurial Podcast: Diary of a CEO

Steven Bartlett sits down with some of the most successful entrepreneurs, peeling back the layers of their personal journeys. Each conversation explores the real challenges, failures, and breakthroughs that shaped their paths in business. This podcast gives listeners honest, raw insights into what it takes to build and sustain a career in the world of entrepreneurship.

6) Best Motivational Podcast: Wayne Dyer Motivation

When you need a dose of encouragement, “Wayne Dyer Motivation” serves as the perfect pick-me-up. Dr. Wayne Dyer’s teachings remind you of the power of mindset, positivity, and self-awareness. His calm voice and practical wisdom leave you feeling lighter, ready to tackle your goals with newfound energy. It’s like having a mentor whispering affirmations in your ear whenever you need it most.

7) Top Comedy Podcast: Bad Friends

“Bad Friends” is where comedy takes the wheel, with Bobby Lee and Andrew Santino’s hilarious, often absurd banter that pushes boundaries in the best way possible. Whether they’re riffing off each other or roasting pop culture, the chemistry between these two is electric. If you need a laugh and enjoy humor that doesn’t shy away from the ridiculous, this podcast is a comedic goldmine.

8) Best Mindfulness Podcast: Joy of Missing Out (JOMO)

In a world obsessed with staying connected, “Joy of Missing Out” celebrates the beauty of disconnecting and living in the moment. It’s a podcast for those who crave mindfulness and intentional living, offering gentle reminders to slow down, breathe, and embrace a simpler, more fulfilling lifestyle. It’s like a breath of fresh air in the cluttered noise of everyday life, reminding you that sometimes less is truly more.

“Ear Biscuits” is a nostalgic trip into the personal lives of Rhett and Link, blending humor and heartfelt stories that often take you back to childhood memories. Their candid conversations touch on everything from friendship to career changes, all with that signature warmth and wit fans love.

10) Best Gaming & Military Humor: Unsubscribe Podcast

The Unsubscribe Podcast is a fun and chaotic show hosted by Eli Doubletap, Donut Operator, Brandon Herrera, and The Fat Electrician. These guys talk about everything from gaming and military stories to random internet happenings. The vibe is casual and full of humor, with plenty of jokes, wild anecdotes, and guest appearances from creators and veterans. The tone is lighthearted but often touches on real-life military experiences, gaming culture, and random internet oddities.

11) Best Mental Health Podcast: Jay Shetty Podcast

Former monk Jay Shetty dives into topics of mental health, relationships, and personal growth with a unique mix of wisdom and modern perspective. The podcast offers actionable advice on how to live a more mindful, balanced life, often featuring guest experts who share their own experiences. It’s ideal for anyone looking to find peace in the chaos of daily life while working on becoming their best self.

12) Best Business and Leadership Podcast: Patrick-Bet David

The PBD podcast is all about dissecting leadership, business strategies, and personal success. Whether he’s breaking down the mindset of top CEOs or interviewing influential leaders, Patrick brings clarity to the complexities of running a business in today’s fast-paced world. It’s insightful, straightforward, and perfect for anyone looking to sharpen their leadership skills.

13) Best Anime and Otaku Culture Podcast: Trash Taste

If you’re an anime fan or just curious about otaku culture, “Trash Taste” offers a hilarious and often insightful look at the quirks of Japanese pop culture. Hosted by three friends, the podcast dives into everything from the latest anime trends to bizarre life experiences in Japan. It’s equal parts informative and entertaining, making it a must-listen for anyone with a love for anime and geek culture.

14) Best Internet Culture Podcast: Violating Community Guidelines

“Violating Community Guidelines” takes a comedic yet critical look at internet culture, exploring the weird, wild, and often troubling corners of the online world. Hosted by Brittany Broski and Sarah Schauer, the podcast isn’t afraid to tackle controversial topics with humor and insight.

15) Best Podcast for Self-Improvement: The Glow Up Secrets

“The Glow Up Secrets” is all about self-improvement, offering a blend of beauty tips, mindset shifts, and personal growth strategies. Each episode feels like a step closer to becoming the best version of yourself, covering everything from wellness routines to mental clarity. If you’re looking for a motivational boost, this podcast serves as a reminder that personal growth is a lifelong journey—one small step at a time.

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